Yes. Although a registration certificate will not be issued until the trademark is in use in commerce, an application to register one with the USPTO may be filed before use begins. An application to register a trademark with the USPTO may be based on either use or intent to use the trademark in commerce. That is to say, you can apply to register a trademark even before you’ve started using it. Before a registration certificate will be issued, however, you will need to demonstrate that use of the trademark in commerce has begun. This is done by filing a Statement of Use or an Amendment to Allege Use with the USPTO within the applicable timeframe.